Uptodate clinical manifestations of a gout among military personnel
The purpose: to conduct a comprehensive analysis of the clinical manifestations of gout among the military personnel of the Armed Forces of Ukraine (according to the data from the medical histories of patients of the cardio-rheumatology department of the National Military Medical Clinical Center "Main Military Clinical Hospital" (NMМCC "ММСН").
Materials and methods. The analysis of 103 medical histories of 92 male patients of the cardio-rheumatology department of the NMМCC "ММСН" with a diagnosis of gout, aged from 27 to 58 years, was carried out by the method of random sampling. To study the age-related characteristics of the course of gout, the patients were divided into two groups: group I - up to 45 years (young age) 40 patients; group II - 46-58 years (middle age) 52 patients. Based on the results of the study, a computer database was formed. Statistical processing was carried out using Microsoft Excel 2007 and the standard statistical package STATISTICA 6.0.
Results. The defeat of the first metatarsophalangeal joint was only in 40.2±5.1% of military personnel (50±7.9 % among the patients in group I and 32,7±6.5% among the patients in group II, p> 0.05) at the time of hospitalization. A significant part of the patients had lesions of the knee (23.9±4.4%) and ankle joints (20.7±4.2%). Сombined lesion of the joints, in particular, the first metatarsophalangeal joint and other joints was observed in 20.7±7.5% of the military personnel in the debut of gout. The diagnosis of gout was made at the first clinical manifestations only in 29.3±4.7% of patients with classical localization of the lesion. Kidney damage was diagnosed among the most patients with gout, in particular, chronic renal failure was detected in 35.9±5.0% (in 15±5.6% of young military personnel and 51.9±6.9% of middle age,p<0,05).
Conclusions. It was found that the majority among the military personnel with gout (59.8±5.1%) had atypical localization of joint lesions, a frequent combination of lesions of the first metatarsophalangeal and other joints. It was found that gout was diagnosed only in 29.3±4.7% of patients at the first clinical manifestations. Kidney damage has been diagnosed in most patients with gout.
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