• O.V. Burlaka Ukrainian military medical academy
  • V.O. Vahner
Keywords: military women, hormonal disorders, war zone stress factors



According to our previous studies, military women in the conditions of the military environment are more receptive to war zone stress-factors then their male colleagues and are more inclined to the development of unconscious psychosomatic problems associated with impaired reproductive health. The aim. Evaluation of the functional state of the reproductive system according to hormonal studies on military women in the zone of armed conflict. Materials and methods. The study included 66 military women whose reproductive hormonal profile for their blood content has been evaluated for: estradiol, testosterone, progesterone, prolactin, and cortisol. The evaluation was held directly during their stay in the military operation area. Results. Аccording to the results of research, statistically significant higher levels of progesterone and prolactin were determined in the military women (U = 17,0 р = 0,001) and (U = 44,0 р = 0,009) compared to levels for civilian women: 8,95 (6,70- 14,38) і 4,25 (3,15-5,20) nmol/l for progesterone and 12,10 (8,48- 17,23) - 7,75 (6,13-9,63) ng/ml for prolactin. The increased levels of progesterone in the first phase of the menstrual cycle were captured in military women in 70,0±20,6% of cases that might testify to the adrenal genesis of hyperprogesteroneemia and reiterate the stress-associated nature of hormonal disorders in this category of patients. Conclusion. The revealed hormonal changes play a significant role in the development of menstrual and reproductive function disorders for military women who are or have returned from the zone of armed conflict. This well-defined problem requires following deepened research.


Бурлака О.В., Верба Н.А., Вагнєр В.О. До питання гендер-специфічної медичної допомоги жінкам військовослужбовцям в сучасних умовах. Військова медицина України. 2019; 19(2): 61-66.

Жінки. Мир. Безпека: Інформаційно-навчальний посібник з ґендерних аспектів конфліктів для фахівців соціальної сфери / Колектив авторів. – Київ, 2017.– 172 с.

Chaban O.S., Bezsheyko V.H., Khaustova O.O., Burlaka O.V., Ryvak T.B., Kyrylyuk S.S.: Gender-related differences of stress reactions in Ukrainian combatants. Farmatsiia. 2018; 65 (2): 3-10.

Барабой В.А., Резніков О.Г. Фізіологія, біохімія і психологія стресу. Київ:Інтерсервіс, 2013. - 314с.

Tolis G., Rombopoulos G., Kaltsas D., Katounda E., Kaltzidou V., Angelopoulos N. Prolactin and Stress. Encyclopedia of Stress. Second Edition. G. Fink (ed). USA: Academic Press. 2007. P. 231–233.

Christian De Geyter, Maria De Geyter, Peter R.Huber, Eberhard Nieschlag and Wolfgang Holzgreve. Progesteron serum levels during the follicular phase of the enstrual cycle originate from the crosstalk between the ovaries and the adrenal cortex. Human Reproduction. 2002;17(4): 933-39.

Onaka T., Takayanagi Y., Leng G. Metabolic and stressrelated roles of prolactin-releasing peptide. Trends Endocrinol. & Metabolism. 2010; 21 (5): 287–293. 34.

Isobe K., Yukimasa N., Nakai T., Takuwa Y. Pituitary adenylate cyclase-activating polypeptide induces gene expression of the catecholamine synthesizing enzymes, tyrosine hydroxylase and dopamine в hydroxylase, through 32, 52-cyclic adenosine monophosphate- and protein kinase Cdependent mechanisms in cultured porcine adrenal medullary chromaffin cells. Neuropeptides. 1996; 30 (2): 167–175

Гаркави Л.Х., Квакина Е.Б., Уколова М.А. Адаптационные реакции и резистентность организма. Изд. 3-е, доп. Ростов- на-Дону: Изд-во Ростовского ун-та. 1990. - 223 с.

How to Cite
Burlaka, O., & Vahner, V. (2019). THE REPRODUCTIVE HEALTH ISSUES OF MILITARY WOMEN IN ASPECTS OF STRESS-ASSOCIATED HORMONAL DISODERS. Ukrainian Journal of Military Medicine, 19(4), 58-63. Retrieved from